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The molecular-biological basis of decidualization of the endometrium from the positions of prevention and treatment of pregnancy loss

Давыдов А. И., Горячкина В. Л., Кузнецова И. В., Мухамедова С. Г.
Вопросы гинекологии, акушерства и перинатологии
Т. 17, Вып. 3, С. 53-58
Опубликовано: 2018
Тип ресурса: Обзор

DOI:10.20953/1726-1678-2018-3-53-58

Аннотация:
The review deals with specificities of interactions between decidual cells and cells of the maternal immune system. Literature data about involvement of decidual cells in initiation of the immune process are presented. The role of decidual cells in the formation of immunological tolerance due to variously secreted and expressed cytokine molecules that control sequential reproductive events has been shown. In the decidual membrane, complex interaction between decidual cells and cells of the maternal immune system occurs, aimed at ensuring immunological tolerance of the «mother-fetus» system. Impairment of this process leads to the development of gestational complications, including loss of a pregnancy. © 2018 Dynasty Publishing House. All rights reserved.
Ключевые слова:
Decidual cells; Decidual membrane; Decidual tissue; Immunological tolerance; Maternal immune cells; Progesterone
Язык текста: Русский
ISSN: 2414-9152
Давыдов А. И. Александр Ильгизирович 1961-
Горячкина В. Л. Валерия Львовна 1939-
Кузнецова И. В. Ирина Всеволодовна 1961-
Мухамедова С. Г. Светлана Галиевна 1952-
Davy'dov A. I. Aleksandr Il`gizirovich 1961-
Goryachkina V. L. Valeriya L`vovna 1939-
Kuznetsova I. V. Irina Vsevolodovna 1961-
Mukhamedova S. G. Svetlana Galievna 1952-
The molecular-biological basis of decidualization of the endometrium from the positions of prevention and treatment of pregnancy loss
Текст визуальный непосредственный
Вопросы гинекологии, акушерства и перинатологии
ООО "Издательство "Династия"
Т. 17, Вып. 3 С. 53-58
2018
Обзор
Decidual cells Decidual membrane Decidual tissue Immunological tolerance Maternal immune cells Progesterone
The review deals with specificities of interactions between decidual cells and cells of the maternal immune system. Literature data about involvement of decidual cells in initiation of the immune process are presented. The role of decidual cells in the formation of immunological tolerance due to variously secreted and expressed cytokine molecules that control sequential reproductive events has been shown. In the decidual membrane, complex interaction between decidual cells and cells of the maternal immune system occurs, aimed at ensuring immunological tolerance of the «mother-fetus» system. Impairment of this process leads to the development of gestational complications, including loss of a pregnancy. © 2018 Dynasty Publishing House. All rights reserved.