International Archives of Allergy and Immunology
Vol.177, Issue4, P. 370-380
Аннотация:
Coeliac disease (CD) is an autoimmune enteropathy triggered by the ingestion of gluten-containing grains in genetically predisposed individuals. Identification of CD in clinical practice is often difficult due to the manifestation of non-specific symptoms and signs, so a relatively significant proportion of CD cases remain undiagnosed. Timely detection of the disease is necessary to provide an appropriate approach to control of the disease treatment, in order to avoid potential complications. This is even more important in the case of children and adolescents, to ensure their proper growth and development. In this review, we discuss the data on the current strategies for CD detection among paediatric populations and the role of questionnaire-based discovery of CD cases in the area of interest. We assume that mass screening is a preferable strategy for finding CD cases within the paediatric population because this could uncover symptomatic, oligosymptomatic, and asymptomatic CD cases. H
Ключевые слова:
Coeliac disease; Paediatric population; Questionnaire; Screening; Symptoms
simvastatin; autoantigen; gluten; abdominal pain; Article; autoimmune disease; awareness; blood sampling; celiac disease; clinical practice; constipation; cost effectiveness analysis; diagnostic test; diarrhea; duodenum biopsy; gastrointestinal symptom; grain; groups by age; health survey; high risk population; HLA typing; human; low risk population; mass screening; pediatrician; periodicity; priority journal; quality of life; questionnaire; serology; symptom; adolescent; autoimmunity; celiac disease; child; early diagnosis; immunology; mass screening; Adolescent; Autoantigens; Autoimmunity; Celiac Disease; Child; Early Diagnosis; Glutens; Humans; Mass Screening; Surveys and Questionnaires
Savvateeva L. V. Lyudmila Vladimirovna 1980-
E`rdes S. I. Svetlana Il`inichna 1958-
Antishin A. S. Anton Sergeevich 1990-
Zamyatnin A. A. Andrej Aleksandrovich 1976-
Савватеева Л. В. Людмила Владимировна 1980-
Эрдес С. И. Светлана Ильинична 1958-
Антишин А. С. Антон Сергеевич 1990-
Замятнин А. А. Андрей Александрович 1976-
Current paediatric coeliac disease screening strategies and relevance of questionnaire survey
Текст визуальный непосредственный
International Archives of Allergy and Immunology
S. Karger AG
Vol.177, Issue4 P. 370-380
2018
Статья
Coeliac disease Paediatric population Questionnaire Screening Symptoms
simvastatin autoantigen gluten abdominal pain Article autoimmune disease awareness blood sampling celiac disease clinical practice constipation cost effectiveness analysis diagnostic test diarrhea duodenum biopsy gastrointestinal symptom grain groups by age health survey high risk population HLA typing human low risk population mass screening pediatrician periodicity priority journal quality of life questionnaire serology symptom adolescent autoimmunity celiac disease child early diagnosis immunology mass screening Adolescent Autoantigens Autoimmunity Celiac Disease Child Early Diagnosis Glutens Humans Mass Screening Surveys and Questionnaires
Coeliac disease (CD) is an autoimmune enteropathy triggered by the ingestion of gluten-containing grains in genetically predisposed individuals. Identification of CD in clinical practice is often difficult due to the manifestation of non-specific symptoms and signs, so a relatively significant proportion of CD cases remain undiagnosed. Timely detection of the disease is necessary to provide an appropriate approach to control of the disease treatment, in order to avoid potential complications. This is even more important in the case of children and adolescents, to ensure their proper growth and development. In this review, we discuss the data on the current strategies for CD detection among paediatric populations and the role of questionnaire-based discovery of CD cases in the area of interest. We assume that mass screening is a preferable strategy for finding CD cases within the paediatric population because this could uncover symptomatic, oligosymptomatic, and asymptomatic CD cases. H