Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan
Franke B., Michelini G., Asherson P., Banaschewski T., Bilbow A., Buitelaar J. K., Cormand B., Faraone S. V., Ginsberg Y., Haavik J., Kuntsi J., Larsson H., Lesh K. Yu., Ramos-Quiroga J. A., Réthelyi J. M., Ribases M., Reif A.
European Neuropsychopharmacology
Vol.28, Issue10, P. 1059-1088
Опубликовано: 2018
Тип ресурса: Обзор
DOI:10.1016/j.euroneuro.2018.08.001
Аннотация:
Attention-deficit/hyperactivity disorder (ADHD) is highly heritable and the most common neurodevelopmental disorder in childhood. In recent decades, it has been appreciated that in a substantial number of cases the disorder does not remit in puberty, but persists into adulthood. Both in childhood and adulthood, ADHD is characterised by substantial comorbidity including substance use, depression, anxiety, and accidents. However, course and symptoms of the disorder and the comorbidities may fluctuate and change over time, and even age of onset in childhood has recently been questioned. Available evidence to date is poor and largely inconsistent with regard to the predictors of persistence versus remittance. Likewise, the development of comorbid disorders cannot be foreseen early on, hampering preventive measures. These facts call for a lifespan perspective on ADHD from childhood to old age. In this selective review, we summarise current knowledge of the long-term course of ADHD, with an
Ключевые слова:
Adult-onset ADHD; Cognitive impairment; Comorbidity; Developmental trajectory; Genetics; Treatment
anxiety disorder; attention deficit disorder; autism; bipolar disorder; cognition; comorbidity; drug dependence; environmental factor; human; illness trajectory; learning disorder; lifespan; long term care; mood disorder; neuroimaging; onset age; phenotype; priority journal; Review; risk factor; tic; treatment response; aging; attention deficit disorder; genetics; psychology; Aging; Attention Deficit Disorder with Hyperactivity; Comorbidity; Humans
Язык текста: Английский
ISSN: 1873-7862
Franke B.
Michelini G.
Asherson P.
Banaschewski T.
Bilbow A.
Buitelaar J. K.
Cormand B.
Faraone S. V.
Ginsberg Y.
Haavik J.
Kuntsi J.
Larsson H.
Lesh K. Yu. Klaus-Peter Yulius 1957-
Ramos-Quiroga J. A.
Réthelyi J. M.
Ribases M.
Reif A.
Франке Б.
Мичелини Г.
Ашерсон П.
Банасчеwски Т.
Билбоw А.
Буителаар Й. К.
Cорманд Б.
Фараоне С. В.
Гинсберг Y.
Хаавик Й.
Кунци Й.
Ларссон Х.
Леш К. Ю. Клаус-Петер Юлиус 1957-
Рамос-Qуирога Й. А.
Рéтхелyи Й. М.
Рибасес М.
Реиф А.
Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan
Текст визуальный непосредственный
European Neuropsychopharmacology
Elsevier Science Publisher B.V.
Vol.28, Issue10 P. 1059-1088
2018
Обзор
Adult-onset ADHD Cognitive impairment Comorbidity Developmental trajectory Genetics Treatment
anxiety disorder attention deficit disorder autism bipolar disorder cognition comorbidity drug dependence environmental factor human illness trajectory learning disorder lifespan long term care mood disorder neuroimaging onset age phenotype priority journal Review risk factor tic treatment response aging attention deficit disorder genetics psychology Aging Attention Deficit Disorder with Hyperactivity Comorbidity Humans
Attention-deficit/hyperactivity disorder (ADHD) is highly heritable and the most common neurodevelopmental disorder in childhood. In recent decades, it has been appreciated that in a substantial number of cases the disorder does not remit in puberty, but persists into adulthood. Both in childhood and adulthood, ADHD is characterised by substantial comorbidity including substance use, depression, anxiety, and accidents. However, course and symptoms of the disorder and the comorbidities may fluctuate and change over time, and even age of onset in childhood has recently been questioned. Available evidence to date is poor and largely inconsistent with regard to the predictors of persistence versus remittance. Likewise, the development of comorbid disorders cannot be foreseen early on, hampering preventive measures. These facts call for a lifespan perspective on ADHD from childhood to old age. In this selective review, we summarise current knowledge of the long-term course of ADHD, with an