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A man's role in recurrent miscarriage in a spouse

Gamidov S.I., Ovchinnikov R.I., Popova A.Y., Golubeva O.N., Ushakova I.V.
Urologiia (Moscow, Russia : 1999)
№ 1 Suppl 1, С. 35-43
Опубликовано: ## 2016
Тип ресурса: Статья; Обзор
Аннотация:
In a review article based on the published literature and their own research, the authors examine the role of a man in recurrent miscarriage and reproductive losses in a spouse. Detailed description is presented of the negative impact of elevated levels of sperm DNA fragmentation on the course of pregnancy, especially during the first trimester, on the occurrence of recurrent miscarriage or missed abortion, on the effectiveness of assisted reproductive technology (ART) programs. The etiology and pathogenesis of damage to sperm DNA are described. Outlined are positive effects of correcting adverse lifestyle factors, the role of varicocelectomy and antioxidant therapy, and advances in ART. The review specifies the role of different male karyotype abnormalities (translocations) in the pathogenesis of pregnancy loss. The implications of urologic surgery, preimplantation genetic diagnosis in solving this problem are discussed. New treatment strategies using correction of male disorders for couples with recurrent miscarriage are offered.
Рубрики Mesh:
Аборт самопроизвольный
Аборт самопроизвольный - диагностика
Аборт самопроизвольный - этиология
Аборт самопроизвольный - патофизиология
Аборт самопроизвольный - профилактика и контроль
Женский
Человек
Мужской
Беременность
Сексуальная дисфункция физиологическая
Сексуальная дисфункция физиологическая - диагностика
Сексуальная дисфункция физиологическая - патофизиология
Сексуальная дисфункция физиологическая - терапия
Журнальная статья
Обзор
Язык текста: Русский
ISSN: 1728-2985
Gamidov S.I.
Ovchinnikov R.I.
Popova A.Y. A Yu
Golubeva O.N.
Ushakova I.V.
Department of Andrology and Urology FSBI Scientific Center for Obstetrics, Gynecology and Perinatology n.a. Academician V.I. Kulakov of RMPH.
Department of Obstetrics, Gynecology, Perinatology and Reproductology of the Institute of Professional Education SBEI HPE First Moscow State Medical University n.a. I.M. Sechenov of RMPH.
Department of Reproduction FSBI Scientific Center for Obstetrics, Gynecology and Perinatology n.a. Academician V.I. Kulakov of RMPH.
A man's role in recurrent miscarriage in a spouse
Текст визуальный электронный
Urologiia (Moscow, Russia : 1999)
№ 1 Suppl 1 С. 35-43
2016
antioxidant therapy
assisted reproductive technologies
male factor infertility
normal karyotype translocation
preimplantation genetic diagnosis
recurrent miscarriage
reproductive losses
sperm DNA fragmentation
varicocele
Статья
Обзор
Abortion, Spontaneous G08.686.784.769.496.125
Abortion, Spontaneous diagnosis G08.686.784.769.496.125
Abortion, Spontaneous etiology G08.686.784.769.496.125
Abortion, Spontaneous physiopathology G08.686.784.769.496.125
Abortion, Spontaneous prevention & control G08.686.784.769.496.125
Аборт самопроизвольный G08.686.784.769.496.125
Аборт самопроизвольный диагностика G08.686.784.769.496.125
Аборт самопроизвольный этиология G08.686.784.769.496.125
Аборт самопроизвольный патофизиология G08.686.784.769.496.125
Аборт самопроизвольный профилактика и контроль G08.686.784.769.496.125
Female
Женский
Humans B01.050.150.900.649.313.988.400.112.400.400
Человек B01.050.150.900.649.313.988.400.112.400.400
Male
Мужской
Pregnancy G08.686.784.769
Беременность G08.686.784.769
Sexual Dysfunction, Physiological C12.100.875
Sexual Dysfunction, Physiological diagnosis C12.100.875
Sexual Dysfunction, Physiological physiopathology C12.100.875
Sexual Dysfunction, Physiological therapy C12.100.875
Сексуальная дисфункция физиологическая C12.100.875
Сексуальная дисфункция физиологическая диагностика C12.100.875
Сексуальная дисфункция физиологическая патофизиология C12.100.875
Сексуальная дисфункция физиологическая терапия C12.100.875
Journal Article V02.600
Журнальная статья V02.600
Review V02.600.500 V02.912
Обзор V02.600.500 V02.912
In a review article based on the published literature and their own research, the authors examine the role of a man in recurrent miscarriage and reproductive losses in a spouse. Detailed description is presented of the negative impact of elevated levels of sperm DNA fragmentation on the course of pregnancy, especially during the first trimester, on the occurrence of recurrent miscarriage or missed abortion, on the effectiveness of assisted reproductive technology (ART) programs. The etiology and pathogenesis of damage to sperm DNA are described. Outlined are positive effects of correcting adverse lifestyle factors, the role of varicocelectomy and antioxidant therapy, and advances in ART. The review specifies the role of different male karyotype abnormalities (translocations) in the pathogenesis of pregnancy loss. The implications of urologic surgery, preimplantation genetic diagnosis in solving this problem are discussed. New treatment strategies using correction of male disorders for couples with recurrent miscarriage are offered.