Filippova T.V.
Alyaev Y.G. Yu G
Rudenko V.I.
Asanov A.Y. A Yu
Gadzhieva Z.K.
Subbotina T.I.
Perekalina A.N.
Department of Medical Genetics.
Department of Urology, Sechenov First Moscow State Medical University, Moscow.
Genetic aspects of urolithiasis
Текст визуальный электронный
Urologiia (Moscow, Russia : 1999)
№ 2 Suppl 2 С. 95-102
2016
molecular genetic diagnostics of urolithiasis
mutations
prevention
urolithiasis candidate genes
Статья
Обзор
Animals B01.050
Животные B01.050
Genetic Predisposition to Disease C23.550.291.687.500 G05.380.355
Генетическая предрасположенность к болезни C23.550.291.687.500 G05.380.355
Humans B01.050.150.900.649.313.988.400.112.400.400
Человек B01.050.150.900.649.313.988.400.112.400.400
Urolithiasis genetics C12.050.351.968.967 C12.200.777.967 C12.950.967
Urolithiasis metabolism C12.050.351.968.967 C12.200.777.967 C12.950.967
Уролитиаз генетика C12.050.351.968.967 C12.200.777.967 C12.950.967
Уролитиаз метаболизм C12.050.351.968.967 C12.200.777.967 C12.950.967
Journal Article V02.600
Журнальная статья V02.600
Review V02.600.500 V02.912
Обзор V02.600.500 V02.912
The article presents summarized results of domestic and international studies of the genetic aspects of urolithiasis. The presented evidence suggests the importance of early and accurate molecular genetic diagnostics of hereditary diseases associated with stone formation for timely treatment and prevention for patients' relatives. Also provided are examples of using molecular genetic diagnostics in urologist's practice for monogenic and multifactorial diseases associated with stone formation. Taken together, these results show that using modern post-genomic technologies for assessing the risk of hereditary predisposition to urolithiasis is justified.