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Docosahexaenoic acid in the treatment of idiopathic male infertility

Vinogradov I.V., Gamidov S.I., Gabliya M.Y., Zhukov O.B., Ovchinnikov R.I., Malinina O.Y., Popova A.Y., Chalyi M.E., Bragina E.E., Zhivulko A.R.
Urologiia (Moscow, Russia : 1999)
№ 1, С. 78-83
Опубликовано: ## 2019
Тип ресурса: Статья
Аннотация:
docosahexaenoic acid is one of the most common fatty acids in the cell membranes of sperm. This substance is a structural component of cell membranes, and is responsible for such properties as plasticity and fluidity which are necessary for the implementation of the process of capacitation and acrosome reaction. In addition, docosahexaenoic acid has antioxidant properties. Aim of our study was to assess the effect of dietary supplement docosahexaenoic acid (Brudi PLUS) on such markers of male fertility as the sperm DNA integrity, standard indicators of semen analysis and cryotolerance in infertile men.
Рубрики Mesh:
Взрослые
ДНК - действие лекарственных препаратов
Докозагексаеновые кислоты
Докозагексаеновые кислоты - терапевтическое применение
Двойной слепой метод
Человек
Бесплодие мужское
Бесплодие мужское - лекарственная терапия
Мужской
Спермограмма
Сперматозоиды - действие лекарственных препаратов
Журнальная статья
Многоцентровые исследования
Рандомизированное контролируемое клиническое исследование
Язык текста: Русский
ISSN: 1728-2985
Vinogradov I.V.
Gamidov S.I.
Gabliya M.Y. M Yu
Zhukov O.B.
Ovchinnikov R.I.
Malinina O.Y. O Yu
Popova A.Y. A Yu
Chalyi M.E.
Bragina E.E.
Zhivulko A.R.
) Department of Urology and Operative Nephrology of Peoples» Friendship University of Russia, , Russia.
) Department of Obstetrics, Gynecology, Perinatology and Reproductology of I.M. Sechenov First Moscow State Medical University of Minzdrav of Russia, Moscow, Russia.
) N.A. Lopatkin Scientific Research Institute of Urology and Interventional Radiology, Moscow, Russia.
) Department of Andrology of National Medical Research Center of Obstetrics, Gynecology and Perinatology named after V.I. Kulakov, Moscow, Russia.
) Scientific Research Institute of Medical Rehabilitation and Balneology, Moscow, Russia.
) Department of Urology and Andrology of M.V. Lomonosov Moscow State University.
) Central laboratory of Scientific Research Institute of A.N. Belozersky Institute of Physico-Chemical Biology of M.V. Lomonosov Moscow State University, Moscow, Russia.
Docosahexaenoic acid in the treatment of idiopathic male infertility
Текст визуальный электронный
Urologiia (Moscow, Russia : 1999)
№ 1 С. 78-83
2019
cryotolerance
docosahexaenoic acid
infertility
polyunsaturated fatty acids
sperm DNA fragmentation
Статья
Adult M01.060.116
Взрослые M01.060.116
DNA drug effects D13.444.308
ДНК действие лекарственных препаратов D13.444.308
Docosahexaenoic Acids D10.212.302.380.410.210 D10.251.355.337.250 D10.627.430.450.375
Docosahexaenoic Acids therapeutic use D10.212.302.380.410.210 D10.251.355.337.250 D10.627.430.450.375
Докозагексаеновые кислоты D10.212.302.380.410.210 D10.251.355.337.250 D10.627.430.450.375
Докозагексаеновые кислоты терапевтическое применение D10.212.302.380.410.210 D10.251.355.337.250 D10.627.430.450.375
Double-Blind Method E05.318.370.300 E05.581.500.300 N05.715.360.325.320 N06.850.520.445.300
Двойной слепой метод E05.318.370.300 E05.581.500.300 N05.715.360.325.320 N06.850.520.445.300
Humans B01.050.150.900.649.313.988.400.112.400.400
Человек B01.050.150.900.649.313.988.400.112.400.400
Infertility, Male C12.100.500.430 C12.100.750.700 C12.200.294.430
Infertility, Male drug therapy C12.100.500.430 C12.100.750.700 C12.200.294.430
Бесплодие мужское C12.100.500.430 C12.100.750.700 C12.200.294.430
Бесплодие мужское лекарственная терапия C12.100.500.430 C12.100.750.700 C12.200.294.430
Male
Мужской
Semen Analysis E01.370.225.992 E05.200.992
Спермограмма E01.370.225.992 E05.200.992
Spermatozoa drug effects A05.360.490.890 A11.497.760
Сперматозоиды действие лекарственных препаратов A05.360.490.890 A11.497.760
Journal Article V02.600
Журнальная статья V02.600
Multicenter Study V03.650
Многоцентровые исследования V03.650
Randomized Controlled Trial V03.175.250.500.500
Рандомизированное контролируемое клиническое исследование V03.175.250.500.500
docosahexaenoic acid is one of the most common fatty acids in the cell membranes of sperm. This substance is a structural component of cell membranes, and is responsible for such properties as plasticity and fluidity which are necessary for the implementation of the process of capacitation and acrosome reaction. In addition, docosahexaenoic acid has antioxidant properties. Aim of our study was to assess the effect of dietary supplement docosahexaenoic acid (Brudi PLUS) on such markers of male fertility as the sperm DNA integrity, standard indicators of semen analysis and cryotolerance in infertile men.